In functional medicine, we always want to be looking upstream and trying to gather as many clues and evidence through testing and intake to determine what is at the root cause of the chronic symptoms in question.
We then work to treat and resolve the underlying problem(s) and this helps to reduce symptoms and restore health long term. But what happens when someone is reacting to or not tolerating the treatment needed to resolve their root cause problems?
This is the biggest challenge I see for those who have MCAS and histamine intolerance. Their immune systems are so hyper-reactive and overly sensitive that they will often have trouble tolerating the treatment needed to resolve the root cause issues like parasites, lyme, SIBO, retroviruses, or mold.
I experienced this personally when I was being treated for Lyme disease and mold illness aggressively for 2 years before knowing that MCAS was playing a role in my symptoms. My MCAS manifested as extreme body pain, even after 2 years of Lyme disease treatment my pain wasn't getting any better, in fact, it was getting worse!! I also found myself becoming very sensitive and reactive to foods, smells, chemicals, EMF's, and even most of the medications and supplements that were treating my illness. I could not tolerate treatment and was just getting sicker and feeling worse.
Figuring out I had MCAS and adding in both pharmaceutical and natural anti-histamines and mast cell stabilizers was a game changer for me. My pain levels dropped slowly, my energy improved, my rashes disappeared and my food reactions lessened. Overtime I finally started to be able to tolerate the treatment I needed to resolve my root causes.
After my personal experience and professionally working with lots of mast cell clients, I now understand that its imperative to get the immune system to calm down and be less reactive before you will be able to tolerate treatment for and resolve what's at the root cause of your MCAS.
My practice is now 90% MCAS patients and every client is unique in what combination of anti-histamines and mast cell stabilizers work to calm down the immune response and be less reactive.
I use special lab testing to help give me clues about each clients bio-individual triggers, metabolism, and root cause issues. This helps me make educated recommendations in the area of natural anti-histamines and mast cell stabilizers that will work for each personal individually.
There are some nuances to choosing the right combination of supplements and it often takes some trail and error. This is why I highly recommend working with a practitioner who knows and understands this well to help guide your choices.
You will want to choose clean formulations with minimal or no fillers. I suggest single active ingredient items so that you know what is helping or hurting you.
If you are someone who has food reactions, you will want to time these items to be taken 15-30 minutes prior to meals. This timing can help to reduce post meal time mast cell reactions.
Lastly, never try more than one of these at the same time. Always try anything that is new to you alone with no other changes or adjustments in food or medications, titrate up to the recommended dose (or your tolerated dose) slowly and then add the next item. I typically recommend a 3 day trial before increasing the dose or adding the next supplement.
Here are the natural options that I use most in my practice...
15 Natural Anti-Histamines & Mast Cell Stabilizers:
These go-to, natural mast cell stabilizers can be used in combination with pharmaceuticals like ketotifen, cromolyn, singular, and over the counter anti-histamines like Benadryl if needed. I highly recommend working with an experienced practitioner who can help you choose the products that meet your needs best.
Always keep in mind these anti-histamines and mast cell stabilizers are not going to fix the underlying, or root problem(s) that are causing the MCA symptoms. They will simply help to lower reactions and calm the immune response down so that you can start to treat the underlying reasons your mast cells are over-stimulated in the first place.
If you want to learn more about my approach for reducing MC reactions and improving root cause treatment tolerance and effectiveness, check out my free online webinar.
9/28/2018 01:19:35 pm
Billie, your info is short and powerful. I really love what your putting out and gain from the knowledge. I like it better than Chris Kresser.
10/1/2018 11:37:25 am
Thanks for the great feedback Sharon!
11/19/2018 03:14:36 pm
Do you have a recording of the webinar?
11/21/2018 07:21:56 am
Hi Justin, Yes I do have the webinar recorded. Here is a link to listen to the recording:https://www.functionaldiagnostichealing.com/mcas-webinar-recordings.html
12/29/2019 10:14:35 pm
Did you ever make that blog post about common root causes of MCAS/Histamine Intolerance?
12/30/2019 06:16:52 am
Hello S - I dont have a blog, but do have a recorded webinar on MCAS that includes a complete discussion on the root causes. Click this link here to check that out:https://www.functionaldiagnostichealing.com/mastcellactivationwebinar.html
Penny Jean Wilson
5/16/2020 02:16:23 pm
5/17/2020 06:41:25 am
5/26/2020 06:05:39 am
Penny - I would love to hear your ideas, too. Can you link your vlog or possibly contact me at email@example.com. Many thanks!
8/4/2020 08:18:37 pm
Penny, I'd love to hear more from you about this as well. My medical training is limited (emergency medicine) so I don't have near the insight that you do. But I have MCAD and have contracted COVID twice. It has been quite the journey, to say the least. And the mast cell impact has been substantial. I searched for you in Facebook, because I'd love to see your vlogs, but wasn't able to find you. And you don't seem to be in the MCAS/COVID Facebook group either. If you're willing, would you reach out and share your vlog? I'd like to compare stories. firstname.lastname@example.org is the best way to reach me.
1/11/2021 11:39:58 pm
11/27/2021 06:25:48 pm
Hi, Penny. How are you?
9/8/2020 02:53:21 pm
I purchased herpes herbal medicine and received it within 7 days and used it as prescribed, I tested negative within 3 weeks use, do not loose hope to contact him early If you need help meet him on his email address dr,email@example.com
11/14/2020 12:55:22 pm
I desperately need help with histamine intolerance/possibly mast cell activation syndrome. I am fighting for my life right now, and I need help figuring out what to do to get better. I need help immediately please. I have been to four doctors, the ER, tried multiple approaches, and I am not getting better. i seem to be sensitive to everything. I know that you are booked up, but I am begging for help. I know that you want to help people...please help me. I would love to have a consultation as soon as possible. I am just struggling so much! Thank you for your time and consideration!
9/2/2022 07:05:44 pm
Had minor symptoms off and on all my life but doctor said was bronchitis. At age 40 was diagnosed with Acute Asthma and treated with slim changes for next 15 year, my health consistently deteriated. Age 50 for next 6 years with abundance of the symptoms of MCAD but not yet diagnosed had 4 anaphylaxis episodes with cardiac arrest and did 3 times....once each year for 4 of those six years. Without intabation I would have died. During those six years had mini strokes symptoms and hospitalized. Doctors had no clue because test came back clean. I finally talked them into checking for food and environmental allergies that I had been asking for over 10 years. I was allergic to over 80% of food from all groups. Look up symptoms of MCAD that was me. Even certain water with inadequate ph levels would trigger anaphylaxis. Took me 3 years to figure out how to cook and what to eat again. First time I went grocery shopping it took over 3 hours reading labels for allergy ingredients. The cost was double and not much to eat. By this time I had stopped taking many medication cause always had issues. In 2016 my last anaphylaxis episode I had enough and made a life altering change. Saw a Holistic Specialist that ran test from the core of my body to the outside skin. Blood...20 vials...every test you can get from blood data, stool, urine, hair cut samples, she viewed my previous medical records from every doctor. I had MCAD, Alpha Gayle, Dysbolia, multiple vitamin and enzyme deficiencies, 2 tick diseases, plus many others cell benefactors that has started to deplete. All of this was causing my cells to see every thing that intered my body from all possibilties as a threat and instead of protecting and healing was throwing out warning signs and killing me by causing anaphylaxis shock and by this time within 5 minutes. It has been 6 years Im now 62. Doing shockingly well. Doctors are stund. My life has deeply changed but Im able to enjoy again with restrictions. Remember you must find out the cause. I read all I can find about MCAD that effects 80% of my body from head to toe. With all the food, physical triggers, and environmental allergies it makes it very difficult to eat and have a productive life ...But Im doing it! Yes, I also got Covid. Had bad flu symptoms, stabbing feeling in brain and put me in deep depression for 2 months. Praise God did not effect my lungs. But worked through it. Treated myself. Doubled up on all natural suppliments and did my own healing regiment and took the time to rest. It is important to educate yourself. Get a Holistic Specialist or a doctor that is receptive to natural healing. They must have education in this field. I took online flyers to all my other doctors to help educate them. Everyone must be aware. Understand as best possible. They must be aware of your do's and dont's! Trust me....MCAD does not like medicine among many others triggers. I have helped many with MCAD through providing education and direction. Send me an email and we can make arrangements to talk. Too much to type. I could have made this text 5 xs longer with all my information. Lets get started. firstname.lastname@example.org
5/14/2023 12:41:16 pm
Did you get help? I have some thoughts.
1/5/2021 08:50:58 am
Which of these natural antihistamines can be taken with salicylat intolerance?
9/2/2022 07:09:28 pm
Babsi, go online in search box and ask that same question. It should show up. Schroll down and search.
1/6/2021 07:55:30 am
If you are salicylate sensitive, the items I recommend starting with are DAO, No-Fenol Enzymes, Nettle Leaf, Vitamin C, Pycnogenol, Baikal Skullcap, L-theanine and GABA. The ones you are less likely to tolerate would be quercetin and luteolin.
2/27/2021 12:15:52 am
Is epstein barr considered a retrovirus?
3/3/2021 07:18:50 am
No, EBV is not a retrovirus
2/28/2021 07:29:01 pm
What was the homeopathic you suggested in your video. Its hard to understand it clearly. Most homeopathics have odd names so im trying to be sure I heard what I heard. Lol
3/3/2021 07:19:37 am
The homeopathic I talked about that can help modulate immune function and reduce the cell danger response is Suramin Homeopathic
1/26/2022 02:27:35 pm
What potency for the Suramin homeopathic? Thanks
1/8/2023 03:44:00 pm
I have been having difficulty finding Suramin Homeopathic. It seems the medicine is not available in the United States. Do you know where it can be purchased?
3/12/2021 05:01:43 pm
I am wondering if any of these are made using corn. Corn is an allergen, severe. Also, if you are allergic to things like apples and latex foods... are any of these things you can have?
3/17/2021 09:16:49 pm
Great content!! So much informative content you produce high quality of content which is good for those people can possibly visit your site. It same as Haarlem Oil and Haarlem Oil for Horses (www.horses-haarlem-oil.com/product-category/shop) made by French people in France. I love the journey of my research from this website. Hope you do more blog post here about health. Thank you and God bless.
5/8/2021 11:14:32 pm
I am pretty sure I have mast cell. At the least a severe histamine intolerance but I get terrible panic attacks from breathing cleaning products and scents, and I have had terrible issues since I had a reaction to an antibiotic two years ago. My biggest issue that I worry about is my heart rate gets funny , it really runs fast. Exercise seems to be a trigger, some foods. And my bp seems to be all over and Sensitive. Any of these other than maybe l-Theanine that might be used to help a histamine induced rapid heart rate?
6/22/2021 12:43:47 am
Hi. Thank you for sharing this very informative and useful article. Btw. I wanna share my experience about Genuine Haarlem Oil for Human since when I was started to using it for my health problems. Their products are very helpful both human and animals good for immune system booster.
7/25/2021 07:28:27 pm
Do you know if DGL licorice contains salicylates? I know that regular licorice does, and am wondering if the removal of glycyrrhizin makes it safe. I'm looking for something to treat gastritis that is low salicylate and oxalate and it's proving very difficult. I have the gastritis from a bad reaction to salicylates.
8/22/2021 09:00:08 am
I WANT TO USE THIS OPPORTUNITY TO SAY A VERY BIG THANK YOU TO DR Ogberaese, My name is Leonard Shirin i am so happy to share this testimony on how Dr.Ogberaese healed me from genital herpes. i was detected with genital herpes around 10th may 2019, and ever since that day i have been looking for a way to end this virus from my body, but the more i try, the more i was told there was no solution. Few months ago i saw a testimony of some people on how Dr Ogberaese cure them from HERPES VIRUS, i also heard about it on media when a young lady also gave her testimony saying Dr Ogberaese cured her oral herpes. I was left with no other hope than to contact Dr Ogberaese and give him a try. I contacted him and told him what i was going through. He said he could heal me, that he is going to send me a herbal medicine and He sent the medicine as he promised. I took this herbal medicine for 1 week and it was obvious that his medicine was for real, because the herpes started clearing from my body. Later at the 2 week, i went for medical check up and i was surprised when my doctor told me he found no trace of the virus in me again. At first when he told me, i was so shock and still did not believed until he gave me my test result. to make my story short i am now free from herpes, after many months of sorrow and my sickness is gone, i thank God for leading me to this man, and i want to also lead you to him if you have any illness like HIV, HPV, hepatitis B, asthma, cancer, Diabetes, COLD SCORE,TOOTH ACHE FIBROID and AUTISM. You can email him on email@example.com or whats-app him on +2348073818653. visit him on his website: https://dr-ogberaese-herbal-home.jimdosite.com
9/10/2021 01:30:22 am
Thank you for sharing this very informative content I read a lot of importance's to live longer by taking self care by drinking food supplements daily. I also recommend Haarlem Oil made from France. It can help to boost your immune system to fight against viruses.
10/14/2021 06:48:35 am
My name is Isi Voorhees from the United Kingdom. I am here to share my experience on how I got cured from genital Herpes through the help of Dr oosa who uses his roots and herbs to cure my Herpes. I am healthy and strong once again. All thanks to you Dr oosa may you live long to continue the good work you started, as many of you out there looking for a solution to your herpes problems kindly contact dr oosa firstname.lastname@example.org or whatsapp +2349134261364
12/6/2021 12:54:14 pm
Can Enzymedica digestive enzymes be taken along with No-Fenol enzyme. Please kindly let me know. Thanks
12/12/2021 05:35:02 am
I CONSUMED TOO MUCH BENZOLATES THEN BECAME SALICYLATE INTOLERANT. I PUT MY FEET IN A BUCKET WITH WARM WATER AND EPSOM SALTS EACH NIGHT AND GOT BACK ON MY FOOD.
10/9/2022 08:53:10 am
Size likely as industry everything why light. Score career just ball whose image stay. Woman kind western require itself although.
10/13/2022 06:10:51 pm
Important force him certain work. How there law decide democratic. Turn including look daughter leader state. Admit fish yeah manage various participant week TV.
11/3/2022 08:39:40 am
Firm difficult language marriage. Hair billion these use key item hotel.
5/18/2023 04:42:26 pm
I have been on anti-histamines for a long time. I have gained so much weight. Do you know if taking these supplements will perpetuate weight gain?
Leave a Reply.
Billie Shellist, FDN-P
I practice functional nutrition, an approach that allows me to look at your entire health history and help you find the "root causes" of your chronic health complaints.
This cuts out the trial and error process and helps you get real symptom relief and resolution!
Food is medicine and knowledge is power -I hope you enjoy my anti-inflammatory recipes which are gluten, dairy, and soy free as well as very low grain and sugar.
If you'd like to heal from the root cause(s) of your chronic symptoms, try starting with a complimentary 15-minute consultation. Click here to request your free session.